Glycobiology

Proteoglycan and Sialic acid

Proteoglycans are more than 95% carbohydrate by weight. Proteoglycan supports to offer us with the knowledge to the molecule's several chemical compositions. As proteo mentions to protein, while glycan signifies sugar or a group of sugars, so proteoglycan is a long polysaccharide chain covalently committed to a protein. The protein element of proteoglycans is manufactured by ribosomes and mostly translocated into the lumen of the rough endoplasmic reticulum. Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone and are found widely distributed in animal tissues and to a lesser level in some additional organisms, ranging from fungi, plants, yeasts and bacteria, mostly in glycoproteins and gangliosides.